The best audio interface with MIDI input gives you a practical way to connect microphones, instruments, studio monitors, and hardware MIDI gear through one central hub. The right model can simplify your setup while improving recording quality, monitoring, and workflow.
We compared 10 interfaces across channel count, connectivity, conversion quality, MIDI support, onboard processing, and expansion options to help you choose the right fit for a compact desk, serious home studio, or growing production rig.
Best 10 Audio Interface with Midi Input Picks for 2026
Best All-Around Pick
- 5-pin MIDI input and output
- Two combo inputs with 48V phantom power
- Loopback and extensive included software
Best For: Home producers, beginners, and compact MIDI setups
Best Budget Compact Option
- USB-C bus-powered design
- 24-bit/192kHz two-channel recording
- Direct monitoring and 3.5mm headphone output
Best For: Mobile creators and simple two-input setups
Best for Expanding Setups
Focusrite Scarlett 4i4 4th Gen
- MIDI I/O with four inputs and four outputs
- Two mic preamps and two Hi-Z inputs
- Auto Gain, Clip Safe, and Air mode
Best For: Growing home studios with multiple instruments and MIDI gear
Best for Large Studios
- 18 inputs and 20 outputs over USB
- Eight MIDAS mic preamps with phantom power
- MIDI and ADAT I/O for expansion
Best For: Bands, larger home studios, and multi-microphone recording
Best Entry-Level Pick
Focusrite Scarlett 2i2 4th Gen
- Two mic preamps and two Hi-Z inputs
- 24-bit/192kHz recording with 120dB dynamic range
- Auto Gain, Clip Safe, and Air modes
Best For: Simple two-channel vocal and instrument recording
Best Compact MIDI Option
- MIDI I/O with 2 x 2 analog audio I/O
- 32-bit integer/192kHz support
- DSP-powered latency-free monitoring
Best For: Compact studios combining MIDI gear with two-channel audio
Best Expandable Studio Pick
- 18 inputs and 16 outputs with MIDI I/O
- Four mic preamps, Hi-Z, line, ADAT, and S/PDIF
- 24-bit/192kHz converters with 122dB dynamic range
Best For: Expanding studios with multiple sources and MIDI gear
Best 4-Input Value
- 4-in/4-out USB connectivity
- Four Midas mic preamps and MIDI I/O
- Up to 24-bit/192kHz support
Best For: Home studios needing four inputs and MIDI
Best Compact Studio Starter
- Compact 2x2 USB-C interface
- Vintage 610 preamp emulation
- MIDI and up to 24-bit/192kHz audio
Best For: Solo creators and mobile recording
Best for Expanded I/O
Yamaha URX44C USB-C Audio/MIDI Interface
- 6-in/4-out USB-C connectivity
- Four combo inputs plus two line inputs
- DSP monitoring effects and MIDI I/O
Best For: Small studios needing flexible routing and effects
Best All-Around Pick – Arturia MiniFuse 2
The Arturia MiniFuse 2 is a practical audio interface with MIDI input for musicians who need a compact setup for vocals, guitar, synths, or drum machines. Its two combo inputs, 5-pin MIDI connections, loopback, and beginner-friendly software make it easy to start recording at home or on the go.
Best For: Home producers, beginners, guitarists, vocalists, and compact MIDI-based setups.
Pros:
- Includes 5-pin MIDI input and output for synths, controllers, and drum machines.
- Two combo mic/line/instrument inputs with 48V phantom power.
- Loopback supports capturing voiceovers alongside in-app or in-game audio.
- Includes Ableton Live Lite, Analog Lab Intro, effects, guitar software, and other creative tools.
Cons:
- Only two main inputs and two balanced line outputs.
- The included software may be more than a simple recording setup needs.
With its approachable workflow, MIDI connectivity, and five-year warranty, the MiniFuse 2 is a strong choice for creators who want flexibility without a complicated studio hub.
Best Budget Compact Option – PIYONE Q2 Alloy Red
The PIYONE Q2 is a compact two-channel audio interface with MIDI input appeal for creators building a straightforward PC or mobile recording setup. It offers USB-C connectivity, 24-bit/192kHz recording, combo inputs, phantom power, and direct monitoring in a portable design.
Best For: Mobile creators, beginner home recordists, guitarists, and simple two-input recording sessions.
Pros:
- USB-C connection provides data transfer and bus power without an external power supply.
- Two XLR/TRS combo inputs support microphones, instruments, and line-level sources.
- 24-bit/192kHz recording and zero-latency direct monitoring.
- Built-in 3.5mm headphone output and illuminated gain controls.
Cons:
- Provides only two input channels for recording.
- The supplied notes do not specify dedicated 5-pin MIDI input or output connections.
This is a sensible pick when portability and simple USB-C recording matter more than a larger connection panel or expanded MIDI hardware integration.
Best for Expanding Setups – Focusrite Scarlett 4i4 4th Gen
The Focusrite Scarlett 4i4 4th Gen is an audio interface with MIDI input designed for producers who need room for microphones, instruments, synths, and line-level gear. It combines MIDI I/O with four inputs, four outputs, two mic preamps, two Hi-Z inputs, and useful recording safeguards.
Best For: Home studios with multiple instruments, synths, drum machines, monitors, and MIDI hardware.
Pros:
- Includes MIDI input and output alongside four inputs and four outputs.
- Two mic preamps, two Hi-Z inputs, and four line inputs accommodate varied gear.
- Auto Gain and Clip Safe help manage recording levels and reduce clipping.
- Air mode adds presence and harmonic drive to vocals and guitars.
Cons:
- Its broader I/O configuration may be unnecessary for basic one- or two-source recording.
- At 2.2 pounds, it is less lightweight than the most portable interfaces.
The Scarlett 4i4 is a versatile middle ground: more expandable than a basic two-channel interface while remaining focused on practical home-studio connectivity and workflow.
Best for Large Studios – Behringer UMC1820
The Behringer UMC1820 is an audio interface with MIDI input for recording environments that need substantial I/O. It provides 18 inputs, 20 outputs, MIDI connectivity, ADAT I/O, and eight MIDAS-designed mic preamps, making it suited to larger microphone and instrument setups.
Best For: Larger home studios, multi-microphone recording, bands, and setups that may expand through ADAT.
Pros:
- Offers 18 inputs and 20 outputs over USB 2.0.
- Includes MIDI connectivity and ADAT I/O for expanded studio integration.
- Eight MIDAS-designed mic preamps with 48V phantom power.
- Supports 24-bit/96kHz recording and works with popular software such as Pro Tools, Ableton Live, and Cubase.
Cons:
- Its larger I/O count is excessive for simple solo recording.
- Maximum sample rate is 96kHz rather than 192kHz.
- The supplied dimensions indicate a wide, less portable unit.
Choose the UMC1820 when channel count and expansion are priorities. Its extensive I/O and ADAT support make it better suited to a permanent studio than a minimalist desktop rig.
Best Entry-Level Pick – Focusrite Scarlett 2i2 4th Gen
The Focusrite Scarlett 2i2 4th Gen is a straightforward audio interface with MIDI input shoppers should approach carefully: its supplied specifications list two mic/instrument inputs, but do not list MIDI I/O. It is better suited to recording microphones and guitar directly through USB-C.
Best For: Home recording with two microphones or instruments, especially for users who want simple setup and strong included software.
Pros:
- Two mic preamps and two Hi-Z instrument inputs
- 24-bit/192kHz recording with a 120dB dynamic range
- Auto Gain, Clip Safe, and Air modes simplify recording
- Includes Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion
Cons:
- The supplied details do not list MIDI input or output
- Only two audio inputs are provided
The 2i2 is a capable compact recording interface, but it is not the right match if MIDI connectivity is essential. Choose it for vocal, guitar, and basic two-channel recording rather than keyboard or controller integration.
Best Compact MIDI Option – Yamaha URX22C
The Yamaha URX22C is a strong fit for shoppers seeking an audio interface with MIDI input in a compact 2-in/2-out format. It combines MIDI I/O with two combo inputs, Class-A D-PRE preamps, DSP monitoring, and USB-C connectivity.
Best For: Small home studios using a MIDI keyboard or other external MIDI gear alongside microphones, instruments, or guitar.
Pros:
- Includes MIDI I/O along with 2 x 2 analog audio I/O
- Two XLR/TRS combo inputs with +48V phantom power and one Hi-Z input
- 32-bit integer/192kHz support and latency-free DSP monitoring
- Includes REV-X reverb, Channel Strip, Guitar Amp Classics, and Steinberg software
Cons:
- Provides only two analog inputs and two main outputs
- The listed warranty is one year and has authorized-retailer and U.S. usage conditions
For a compact setup that genuinely includes MIDI connectivity, the URX22C is more directly aligned with this keyword than the Scarlett 2i2. Its limited I/O is best suited to smaller recording rigs rather than expanding multi-mic sessions.
Best Expandable Studio Pick – Focusrite Scarlett 18i16
The Focusrite Scarlett 18i16 is the most flexible audio interface with MIDI input in this group. It offers MIDI I/O alongside 18 inputs and 16 outputs, four mic preamps, Hi-Z and line inputs, ADAT, and S/PDIF for a more expandable studio workflow.
Best For: Producers and recording setups that need MIDI plus multiple microphones, instruments, line-level sources, or future digital expansion.
Pros:
- Includes MIDI I/O, ADAT, S/PDIF, four mic preamps, and eight line inputs
- Two Hi-Z inputs support direct guitar and instrument recording
- 24-bit/192kHz converters with a 122dB dynamic range
- Auto Gain, Clip Safe, and Air modes support a faster recording workflow
Cons:
- Its larger 18-in/16-out design may be more than a basic two-channel setup requires
- Requires an external power supply
The 18i16 is the strongest choice here for a growing studio that needs MIDI and broad audio connectivity. Its extensive I/O makes it less minimal than a compact interface, but far more suitable for complex recording and routing needs.
Best 4-Input Value – Behringer U-PHORIA UMC404HD
Behringer U-PHORIA UMC404HD 4x4 USB Audio Interface, 24-Bit/192kHz, with 4 Midas Mic Preamps
Check Price On AmazonIf you need an audio interface with MIDI input and enough connectivity for a small recording setup, the Behringer U-PHORIA UMC404HD offers four inputs and four outputs, four Midas mic preamps, and support for up to 24-bit/192kHz audio. It connects over USB and works with macOS and Windows.
Best For: Home studios, keyboard players, and musicians who need four simultaneous inputs plus MIDI I/O.
Pros:
- Four-in/four-out design supports multi-source recording and routing.
- Includes four mic preamps and MIDI input/output.
- Supports up to 24-bit/192kHz audio and works with Windows and macOS.
Cons:
- Its 2.7-pound chassis is less portable than smaller two-channel interfaces.
- The supplied notes do not specify included recording software.
The UMC404HD is a practical choice when input count matters more than compact size. Its four preamps and MIDI connectivity make it particularly flexible for larger home-recording setups.
Best Compact Studio Starter – Universal Audio Volt 2
The Universal Audio Volt 2 is a compact audio interface with MIDI input for musicians, podcasters, and streamers. Its 2×2 USB-C design provides two channels, up to 24-bit/192kHz quality, and a Vintage mode designed to emulate the sound of UA’s classic 610 preamps.
Best For: Solo musicians, podcasters, and mobile creators who want a portable two-channel interface with MIDI and bundled studio tools.
Pros:
- Compact 2×2 USB-C interface weighs 650 g.
- Vintage mode offers 610 tube-preamp emulation.
- Supports Mac, Windows, iPad, and iPhone recording, with LUNA and additional software options.
Cons:
- Two channels provide less expansion than four- or six-input alternatives.
- Mobile iOS use may require an external power supply and Apple Lightning to USB Camera Adapter, depending on the device.
Choose the Volt 2 when portability and an approachable recording workflow are priorities. Its two-channel layout suits individual performers, while MIDI and broad device compatibility leave room for keyboard-based setups.
Best for Expanded I/O – Yamaha URX44C USB-C Audio/MIDI Interface
For a more expandable audio interface with MIDI input, the Yamaha URX44C combines six-in/four-out connectivity with four combo inputs, two line inputs, MIDI I/O, and USB-C. It supports 32-bit integer/192kHz audio and adds DSP-powered monitoring effects for more flexible recording.
Best For: Musicians and small studios that need multiple input types, four outputs, and built-in monitoring effects.
Pros:
- Six-input/four-output configuration includes four combo inputs and two line inputs.
- Class-A D-PRE preamps, +48V phantom power, MIDI I/O, and HI-Z support broaden its use.
- DSP-powered monitoring includes REV-X reverb, Channel Strip, and Guitar Amp Classics.
- Includes Cubase AI, Steinberg Plus, and dspMixFx software support.
Cons:
- Its expanded I/O may be more than a simple two-channel setup requires.
- The supplied notes specify a one-year manufacturer warranty limited to qualifying authorized-retailer purchases in the United States.
The URX44C is the strongest fit here for users planning a larger or more varied setup. Its combination of six inputs, four outputs, MIDI, and latency-free DSP monitoring provides useful flexibility for instruments and microphones.
How We Picked the Best Audio Interface with Midi Input
We focused on interfaces that combine reliable audio recording with standard MIDI connectivity, including models suited to solo creators and larger multi-input studios. Our comparison considered input and output counts, microphone preamp quality, USB connectivity, supported sample rates, monitoring controls, driver and software support, and expansion options such as ADAT.
Because product configurations can vary by retailer or region, confirm the current specifications before buying—especially MIDI ports, included software, USB compatibility, and the number of simultaneous inputs.
Quick Comparison
| Best For | Recommended Type | What to Prioritize |
|---|---|---|
| Solo recording and beginners | Compact 2-in/2-out interface | Easy controls, dependable drivers, and MIDI I/O |
| Synths and small hardware setups | 2-in/2-out or 4-in/4-out model | Dedicated MIDI ports and enough line outputs |
| Small bands and multi-mic sessions | 4-input interface | Multiple preamps, headphone monitoring, and routing |
| Large home studios | 8-input interface | High channel count, ADAT expansion, and flexible I/O |
Key Buying Factors for an Audio Interface with Midi Input
Inputs and Outputs
Count the microphones, instruments, and hardware devices you will connect at the same time. Combo XLR/TRS inputs are versatile, while dedicated line outputs matter if you use multiple monitor pairs, external effects, or a hardware mixer.
MIDI Connectivity
Look for standard five-pin MIDI In and Out when connecting keyboards, drum machines, or rack gear. MIDI support is separate from audio recording, so verify that the listed interface includes the ports and routing features you need.
Audio Quality and Latency
24-bit recording is sufficient for most projects, while higher sample-rate support can benefit specialized workflows. More important for everyday use are stable drivers, direct monitoring, responsive headphone output, and low-latency performance.
Expansion and Software
ADAT can add microphone channels later, making an interface more useful as your studio grows. Bundled DAW, instrument, and effects software may also reduce setup costs, but confirm compatibility with your computer and operating system.
Who Should Buy Which Audio Interface with Midi Input?
Choose a compact 2-in/2-out model if you record vocals, guitar, a single keyboard, or occasional MIDI parts. It is usually the simplest and most affordable choice for beginners, songwriters, and mobile setups.
Step up to a four-input interface if you regularly record stereo instruments, multiple synthesizers, or two performers at once. A larger eight-input model is better for drum microphones, full-band tracking, and studios that need room to expand.
For hardware-heavy production, prioritize dedicated MIDI ports, flexible line outputs, and clear routing controls. If you expect your setup to grow, paying more for expansion support and additional I/O can be less expensive than replacing a compact interface later.